The best treatment for heavy knocking on the head may be relevant to the nose spray quickly. The researchers found the basic evidence in the rat that the treatment of the antibodies that sent the nose can reduce the damage of the brain caused by the impact and more severe injuries.
Scientists at Mass General Brigham Published Thursday in Natural neurology– In a rat that is injured in the brain, the experiment seems to improve the natural acute treatment process of the brain while reducing damaged inflammation later. This finding may lead to the prevention of real diseases on the long -term effects of brain injuries, wounds and other conditions, such as the researchers.
The injury to the brain or TBIS is a public health problem continuously. According to the data of the Disease Control and Prevention Center, there are more than 200,000 Americans. Go to the hospital At TBI in 2020, while nearly 70,000 died Scientists also learn that TBIS, including mild things that we call impact, can cause nervous system problems. Increase the risk of dementia Later decade
While there is a way to reduce acute dangers caused by TBIS, such as many relaxation for impact or severe surgery. There is no drug established to prevent its chronic effects. (Which says that brain rehabilitation is often imported However, in recent years, many researchers BRIGHAM have studied antibodies made from experimental laboratory called Foralumab, which shows the contract for neurological conditions such as Many of the blood vessels Therefore, they decided to see if the Foralumab may be useful for TBIS or not.
Viralumab developed by Tiziana Life Sciences. Targeting the specific protein group that interacts with the immune system called CD3. This CD3 suppression of the previous work of the team has. AdviceIncrease the activity of some immune cells called the TREG. If the name has meaning, these cells will help control the response of the immune system to ensure that it will not be confused.
“The injury in the brain is an important cause of death and disability. -Reduction of knowledge and understanding -and chronic inflammation is one of the important reasons. statement From general mass
In their latest rat studies, the researchers found that Foralumab – through the increased activities of the training – the instant improvement of the brain from the pain injuries of the Microglia that uses drugs. (Protection of immunity, the first line that is unique to the brain) is better to eat and clean after damaged cells such as After that, the drug appeared to prevent chronic Microglia from being compared to rats in a rat control group that has been treated with viralumab to three days after the improvement of the car and coordination.
“These findings indicate that being an anti -nose agent CD3 that has a new treatment that is approaching TBI and other types of brain injuries.” The researchers wrote.
Studies in rats and other animals are just the first step in proving that new drugs or vaccines can work according to their hopes. Clearly, more research is needed to check the potential of the drug TBI, but the FORALUMAB has shown previous positive results in human experiments for MSWith other experiments for Alzheimer and The side of the sides of amyotrophic Start or soon to proceed That makes the hope that this antibodies can become a new treatment option and necessary for many brain conditions, including TBI.