Week 15 TNF 49ers vs. Rams Start 'Em Sit 'Em Picks feat. Kyren Williams, Puka Nacua, Deebo Samuel


Week 15 of the 2024 fantasy football season begins with Thursday Night Football. Los Angeles Rams and the San Francisco 49ers. This is an important NFC West matchup with playoff implications. Here are some of the best targets and faders for fantasy teams this week.

Week 15 49ers vs Rams TNF Fantasy Football Start 'Em picks

Week 15 beginsWeek 15 begins
Week 15 begins

Kyren Williams is having an incredibly consistent 2024 fantasy football season, finishing as RB27 or better in all 13 games played so far. He has also been ranked among the weekly top ten players four times, including each of the last two weeks, leading to his current overall ranking of RB7 this year. He is an elite lineup choice this week against San Francisco 49ersdespite facing a strong defense.

Want to predict NFL playoff scenarios? Try ours NFL Playoff Predictor for real-time simulations and stay ahead of the game!

Puka Nacua ranked among the weekly top 20 wide receivers in six of the seven games since his return Los Angeles Rams after an injury. He's also coming off his best game of the year, setting season highs with 17 touchdowns on 19 targets for 178 yards and two total touchdowns. Buffalo Bills. His consistent output and positive momentum make him one of the best overall wide receivers for the lineup this week.

It should start

  • Kyren Williams
  • Puka Nacua
  • Cooper coup
  • George Kittle

DFS Options

  • Brock Purdy
  • Matthew Stafford
  • Juan Jennings

Week 15 49ers vs Rams TNF Fantasy Football Sit 'Em Picks

The 15th week is sittingThe 15th week is sitting
The 15th week is sitting

Deebo Samuel has been unproductive in fantasy football lately. He has failed to pass 25 receiving yards in each of his last four games and has gone eight consecutive weeks without a touchdown. The 49ers use more of their other offensive weapons than Samuel, making him the obvious underdog in the Week 15 lineup, especially with the fantasy playoffs starting this week in most leagues.

He joins her Blake Choirhas yet to establish a big enough role with the Rams to provide much fantasy value. The rookie has eight carries in each of the past two games, matching a season high, but hasn't finished in the top 40 rushers in any game so far. He simply can't be trusted unless his role in fantasy teams continues to grow.

He must sit

  • Blake Choir
  • Deebo Samuel
  • Colby Parkinson
  • DeMarcus Robinson

DFS is off

  • Isaac Guerendo
  • Patrick Taylor
  • Deebo Samuel