Tottenham's injury curse has struck again with Dominic Solanke suffering a knee problem in training.
Solanke was injured on Saturday against Spurs Great week trip to Everton, and it is not yet known how long he will be out of action.
The Spurs striker has been a consistent performer since his £65m summer move from Bournemouth, scoring 11 goals in all competitions.
Speaking ahead of kick-off at Goodison Park, manager Ange Postecoglou said: “Dom tweaked his knee in training yesterday trying to get a kick. I'm not sure to what extent.
“It's always a blow when you lose key players and obviously in the situation we're in it shows that we don't really have the depth to cover that.”
Tottenham have been plagued by injuries this term, with most of their first line – goalkeeper Guglielmo Vicario, Destiny Udogie, Cristian Romero and Micky van de Ven out of action.
Brennan Johnson and Yves Bissouma both picked up knocks against Arsenal last time out and Postecoglou said Bissouma's problem was “not that bad, Brennan's is probably a bit more significant”.
He added: “But we have 11 fit players and that's enough to start the game.”
Tottenham injury absent
- William Vicar (ankle)
- Destiny Udogie (thigh)
- Timo Werner (thigh)
- Rodrigo Bentancur (Head)
- Cristiano Romero (thigh)
- Micky van de Ven (thigh)
- Fraser Forster (illness)
- Brennan Johnson (shin/heel)
- Yves Bissouma (not listed)
- Wilson Odobert (thigh)